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Novel Drug Delivery Systems

By Dr. Sathish Dyawanapelly   |   Institute of Chemical Technology, Mumbai
Learners enrolled: 1140   |  Exam registration: 44
ABOUT THE COURSE:

This course will provide the understanding of design, development and evaluation of various Novel Drug Delivery Systems (NDDS) includes, nanocarriers (polymeric, lipid, metal), controlled drug delivery systems, targeted delivery, mucosal delivery, implantable delivery, transdermal delivery, gastro-retentive delivery, intranasal, pulmonary, ocular, intrauterine delivery system for delivery of drugs and biological molecules such as DNA, siRNA, proteins and peptides. It also covers the scalability and regulatory perspective of NDDS. The NDDS course is designed based on the B. Pharmacy and M. Pharmacy syllabi approved by the Pharmacy Council of India (PCI), which are adopted uniformly by all pharmacy institutions and Universities throughout India. All other learners who want to learn the basics of targeted drug delivery and nanopharmaceuticals can gain vital benefits from this course. 

Course Outcome: 
By the end of the course, you should be able to………
1.        Understand various approaches for the development of Novel Drug Delivery Systems
2.        Describe the criteria for selection of drugs and inactive ingredients for designing NDDS
3.        Appreciate the formulation, evaluation, and applications of various NDDS

INTENDED AUDIENCE: B. Pharmacy, B. Tech Pharmacy, M Pharmacy, M. Tech Pharmaceutical Technology, M. Tech Pharmaceutical Biotechnology, and PhD in Pharmacy/Pharmaceutical Technology, faculty members of all pharmacy disciplines. UG, PG, PhD, research students, faculty members, industry employees, and research scientists in biotechnology, chemistry, material science, and metallurgy, surgeons, clinicians, dentists, and other allied disciplines 

PREREQUISITES: A course in pharmacy, nanoscience, basics of Bioscience, and Bioengineering



INDUSTRY SUPPORT: All Pharmaceutical, Biotechnology, Implants, devices, Biomaterials Industries.
Summary
Course Status : Upcoming
Course Type : Core
Language for course content : English
Duration : 12 weeks
Category :
  • Chemical Engineering
  • Polymers and Colloidal Materials
Credit Points : 3
Level : Undergraduate/Postgraduate
Start Date : 21 Jul 2025
End Date : 10 Oct 2025
Enrollment Ends : 28 Jul 2025
Exam Registration Ends : 15 Aug 2025
Exam Date : 01 Nov 2025 IST
NCrF Level   : 4.5 — 8.0

Note: This exam date is subject to change based on seat availability. You can check final exam date on your hall ticket.

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Course layout

Week 1: Introduction to Novel Drug Delivery Systems 
    •        Fundamentals of Drug Delivery Systems-I
    •        Fundamentals of Drug Delivery Systems-II
    •        Polymers used in Drug Delivery Systems
    •        Selection of polymers in DDS
    •        Commonly used Polymers in DDS

Week 2: Nanoparticles as Drug Delivery Systems-I
   •        Introduction on Nanoparticles as Drug Delivery System-I
   •        Introduction on Nanoparticles as Drug Delivery System-II
   •        Polymer-based nanocarriers  
   •        Introduction on Lipid-based nanocarriers-I
   •        Introduction on Lipid-based nanocarriers-II
   •        Case study

Week 3: Nanoparticles as Drug Delivery Systems-II
   •        Nanostructured Lipid Carriers (NLCs)
   •        Vesicular Drug Delivery Systems-I
   •        Vesicular Drug Delivery Systems-II
   •        Inorganic- Based Nanocarriers
   •        Evaluation of Nanocarriers
   •        Case study

Week 4: Targeted Drug Delivery Systems (TDDS)
   •        Introduction of Targeted Drug Delivery
   •        Targeted Drug Delivery Strategies 
   •        Stimuli-responsive and Multifunctional Approach in TDDS
   •        Tumor Targeted Drug Delivery
   •        Brain Targeted Delivery Systems
   •        Case study

Week 5: Controlled Drug Delivery Systems (CDDS)
   •        Introduction to CDDS
   •        Approaches to design-controlled release formulations-I
   •        Approaches to design-controlled release formulations-II
   •        Approaches to design-controlled release formulations-II
   •        Approaches to design-controlled release formulations-II
   •        Evaluation Parameters of CDDS
   •        Case study

Week 6: Gastroretentive Drug Delivery Systems (GRDDS) and Microencapsulation 
   •        Introduction to GRDDS
   •        Approaches to design GRDDS-I
   •        Approaches to design GRDDS-II
   •        Evaluation Parameters of GRDDS
   •        Methods of microencapsulation and applications
   •        Case study

Week 7: Mucosal and Nasopulmonary Drug Delivery Systems
   •        Introduction to Mucosal Drug Delivery System
   •        Mucoadhesive polymers, Principles of bioadhesion/Mucoadhesion 
   •        Routes of administration, Factors affecting Mucoadhesion 
   •        Formulation considerations of buccal delivery systems
   •        Formulation of Nasopulmonary Delivery Systems, Nose-to-Brain Delivery
   •        Evaluation parameters 
   •        Case study 

Week 8: Ocular Drug Delivery Systems (OCDDS)
   •        Introduction to Ocular Drug Delivery Systems
   •        Ophthalmic Drug Forms 
   •        Formulation considerations
   •        Evaluation parameters 
   •        Case study

Week 9: Transdermal Drug Delivery Systems
   •        Introduction to TDDS
   •        Formulation considerations
   •        Components used in TDDS
   •        Evaluation parameters 
   •        Case study 

Week 10: Intrauterine and Implantable Drug Delivery Systems
   •        Introduction to IUDs 
   •        Development and applications of IUDs
   •        Formulation of Implantable Drug Delivery Systems
   •        Concept of implants 
   •        Evaluation parameters 
   •        Case study

Week 11: Protein/Peptide and Nucleic Acid Delivery Systems
   •        Introduction
   •        Barriers for delivery 
   •        Formulation strategies for delivery 
   •        Evaluation parameters 
   •        Case study

Week 12: Scalability and Regulatory Aspects of Drug Delivery Systems
   •        Current Issues of Scalability and Regulatory Aspects 
   •        Scalable Technologies for Formulating Drug Delivery Systems
   •        Regulatory considerations 
   •        Future directions on Scalability and Regulatory Aspects 
   •        Case study

Books and references

  1.  Y W. Chien, Novel Drug Delivery Systems, 2nd edition, revised and expanded, Marcel Dekker, Inc., New York, 1992.
  2.  Robinson, J. R., Lee V. H. L, Controlled Drug Delivery Systems, Marcel Dekker,Inc., New York, 1992.
  3.  Encyclopedia of controlled delivery, Editor- Edith Mathiowitz, Published by WileyInterscience Publication, John Wiley and Sons, Inc, New York/Chichester/Weinheim
  4.  N.K. Jain, Controlled and Novel Drug Delivery, CBS Publishers & Distributors, New Delhi, First edition 1997 (reprint in 2001).
  5.  S.P.Vyas and R.K.Khar, Controlled Drug Delivery - concepts and advances,Vallabh Prakashan, New Delhi, First edition 2002.
  6.  Devarajan, Padma V., and Sanyog Jain, eds. "Targeted drug delivery: concepts and design." (2015).

Instructor bio

Dr. Sathish Dyawanapelly

Institute of Chemical Technology, Mumbai
Dr. Sathish Dyawanapelly is working as an Assistant Professor (Pharmaceutics) at the Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology (ICT/UDCT), Mumbai, India. He has been actively involved in teaching and research in the Design and Development of Drug Delivery Systems, Nanomedicines, and Nutraceuticals. He has more than 7 years of teaching experience in Novel Drug Delivery Systems, Pharmaceutical Formulation Technology, and Industrial Pharmacy. He has published over 30 research and review articles in peer-reviewed international journals and authored or co-authored numerous book chapters. He developed and transferred 3 different Technologies to Industries. He received one granted patent on “Stable water-soluble formulations of nutritional supplements and preparation methods thereof (Patent number: 563700)”.

He is an Editor for the book entitled “Advances in Stimuli-responsive Nanosystems for Cancer Therapy”, Springer Nature Group [Under Review]. He is an Editorial member for Scientific Reports (Nature), PLOS ONE, Frontiers in Drug Delivery, Discover Pharmaceutical Sciences (Springer), and Current Indian Science (Bentham Science). He serves as a reviewer of peer-reviewed international journals, namely, Carbon, PLOS One, International Journal of Pharmaceutics, International Journal of Nanomedicine, Carbohydrate Polymers, Journal of Ocular Pharmacology and Therapeutics, Current Eye Research, AAPS PharmSciTech, and Journal of Nanomedicine & Nanotechnology.

For more information:


Course certificate

The course is free to enroll and learn from. But if you want a certificate, you have to register and write the proctored exam conducted by us in person at any of the designated exam centres.
The exam is optional for a fee of Rs 1000/- (Rupees one thousand only).
Date and Time of Exams: November 01, 2025 Morning session 9am to 12 noon; Afternoon Session 2pm to 5pm.
Registration url: Announcements will be made when the registration form is open for registrations.
The online registration form has to be filled and the certification exam fee needs to be paid. More details will be made available when the exam registration form is published. If there are any changes, it will be mentioned then.
Please check the form for more details on the cities where the exams will be held, the conditions you agree to when you fill the form etc.

CRITERIA TO GET A CERTIFICATE

Average assignment score = 25% of average of best 8 assignments out of the total 12 assignments given in the course.
Exam score = 75% of the proctored certification exam score out of 100

Final score = Average assignment score + Exam score

Please note that assignments encompass all types (including quizzes, programming tasks, and essay submissions) available in the specific week.

YOU WILL BE ELIGIBLE FOR A CERTIFICATE ONLY IF AVERAGE ASSIGNMENT SCORE >=10/25 AND EXAM SCORE >= 30/75. If one of the 2 criteria is not met, you will not get the certificate even if the Final score >= 40/100.

Certificate will have your name, photograph and the score in the final exam with the breakup.It will have the logos of NPTEL and IIT Bombay .It will be e-verifiable at nptel.ac.in/noc.

Only the e-certificate will be made available. Hard copies will not be dispatched.

Once again, thanks for your interest in our online courses and certification. Happy learning.

- NPTEL team


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