Electronic Systems for Cancer Diagnosis

By Prof. Hardik Jeetendra Pandya | IISc Bangalore

Learners enrolled: 2626 | Exam registration: 1355

ABOUT THE COURSE:

This course is designed with an aim of educating students on the process flow for designing electronic systems for tissue-based cancer diagnosis. An exposure towards developing strategies to discriminate pathological cells from normal ones based on the electrophysiological properties of cells. Design and integrate biochip with electronic module for understanding the electro-thermo-mechanical properties of tissues. microtechnology and its use to fabricate sensors and systems. Students will have an exposure towards how to fabricate the sensors and its application in real world. Several examples of engineering devices used in clinical research will be also covered. Both conventional (class 1000) and non-conventional (class 10000) clean room and some equipment within it will also be shown. Below are some of the course outcomes.The first objective of this course is to understand cancer and its properties: Breast Cancer and Oral CancerThe second objective is to educate the students on the process flow for designing electronic systems for tissue-based cancer diagnosisThe third objective is to develop skills to design electronic systems for cytology-based studiesFourth objective is to develop skills to integrate biochips with electronic system for cancer diagnosisThe fifth objective is to understand how to work in a conventional (class 1000) and non-conventional (class 10000) clean room environment and understand several equipmentsThe final objective is to learn and understand in detail how to design electronic systems with the preexisting knowledge of basic electronics and to add on the 3D printing skills.

INTENDED AUDIENCE : Engineering Students, Faculty from Engineering Colleges

PREREQUISITES : Basic Electronics/Microfabrication

Summary

Course Status :	Completed
Course Type :	Elective
Language for course content :	English
Duration :	12 weeks
Category :	Electrical, Electronics and Communications Engineering
Credit Points :	3
Level :	Undergraduate/Postgraduate
Start Date :	22 Jul 2024
End Date :	11 Oct 2024
Enrollment Ends :	05 Aug 2024
Exam Registration Ends :	16 Aug 2024
Exam Date :	27 Oct 2024 IST

Note: This exam date is subject to change based on seat availability. You can check final exam date on your hall ticket.

Page Visits

Course layout

Week 1  : Introduction to tissue related cancers (Focusing on Breast Cancer and Oral Cancer)Current Gold Standards

Week 2  : Understanding the change in cells or tissue morphology.Developing strategies for diagnosis based on Morphology changes.

Week 3  : Basics of tissue culture methods: Types of cell growth, Work area and equipment (Laminar flow hoods, CO2 incubators, Microscopes, Preservation, Vessels, Storage)

Week 4  : Maintaining cells (harvesting, media and growth requirements), Safety considerations, Cell counting

Week 5  : Understanding 3D Printing and its use as packaging and press-fit contacts in electronic systems for cancer diagnosis

Week 6  : Hands-on experience in designing a 3D printed casing for electronic system packaging

Week 7  : Process for designing electronic system for early diagnosis of cancer based on tissue images

Week 8  : Process for designing electronic systems for cytology studies (cell extraction, scanning and image capturing).

Week 9  : Electronic Systems integrated with Biochip for understanding change in electro-thermo-mechanical properties of tissue

Week 10  : Working in a Clean Room (non-conventional Class 10000) and inspection of Cancer Diagnosis Tool with a basic training of operating the tools

Week 11  : Hands-on experience on lithography

Week 12  : Hands-on experience on wet-bench

Books and references

Lecture notes on some topics will be provided by the instructorJ.D. Plummer, M.D. Deal, P.G. Griffin, Silicon VLSI Technology, Pearson Education, 2001.S.A. Campbell, The Science and Engineering of Microelectronic Fabrication, Oxford University Press, 2001.S.M. Sze (Ed), VLSI Technology, 2nd Edition, McGraw Hill, 1988Senturia S. D., Microsystem Design, Kluwer Academic Publisher, 2001Madou, M Fundamentals of Microfabrication, CRC Press, 1997.Gad-el-Hak, M., Ed.; The MEMS Handbook; CRC Press: New York, NY, 2002.Mather J. P., Roberts P. E., Introduction to Cell and Tissue Culture, Springer, 1997.M. C. Phelan, UNIT 1.1 Basic Techniques for Mammalian Cell Tissue Culture, John Wiley and Sons, Inc, 2001.

Instructor bio

Prof. Hardik Jeetendra Pandya

IISc Bangalore

Prof. Hardik J. Pandya joined the Department of Electronic Systems Engineering (DESE), Indian Institute of Science, Bangalore, in January 2017. Prof. Pandya is leading three laboratories in DESE focused on developing a new class of biomedical devices and technologies. Before joining IISc, he worked as a postdoctoral scientist in the Department of Mechanical Engineering, Maryland Robotics Center, University of Maryland, College Park (2012-2016) and in the Department of Medicine, Brigham and Women’s Hospital–Harvard Medical School (2016-2017). He obtained his Ph.D. from the Indian Institute of Technology Delhi (2013). His current research focuses on minimally invasive and non-invasive technologies with an emphasis on but not limited to cancer diagnosis (brain, breast, head and neck), e-nose (diabetes, breast cancer screening), and Neuroprotective Therapies for Acute Stroke and Epilepsy. His work has resulted in twelve patents (nine filed and three awarded), three book chapters, and around fifty publications in peer-reviewed journals (IEEE TBME, IEEE TBioCAS, Sensors and Actuators B, Lab on a Chip, Biosensors and Bioelectronics, PLOS One, Clinical Biomechanics, Journal of Breath Research, ACS Applied Materials & Interfaces, IEEE Journal of Microelectromechanical Systems, Journal of Micromechanics and Microengineering, Materials Science in Semiconductor Processing, Microscopy and Microanalysis) and conferences. His work has been highlighted as “Breaking Research News” by The Physicians Committee for Responsible Medicine. The work on portable cancer diagnosis tool was featured on Science Translational Medicine as an Editorial Choice, Breast Cancer Diagnosis, March 2016 and has been highlighted on CapeRay blog as “Biochips and Diagnostic tools” in April 2016. His group consisting of twenty-four research scholars (two postdoctoral fellow, ten Ph.D. students, four M.Tech. students, and eight project assistants) is actively working with 20 clinicians on several projects in the medical domain. He is a recipient of the prestigious Early Career Research Award from the Science and Engineering Research Board, Government of India, in 2017. Prof. Pandya is also serving as a non-executive Director (Technical advisor) to two Indian Medical Technology companies.

Course certificate

The course is free to enroll and learn from. But if you want a certificate, you have to register and write the proctored exam conducted by us in person at any of the designated exam centres.
The exam is optional for a fee of Rs 1000/- (Rupees one thousand only).
Date and Time of Exams: 27 October 2024 Morning session 9am to 12 noon; Afternoon Session 2pm to 5pm.
Registration url: Announcements will be made when the registration form is open for registrations.
The online registration form has to be filled and the certification exam fee needs to be paid. More details will be made available when the exam registration form is published. If there are any changes, it will be mentioned then.
Please check the form for more details on the cities where the exams will be held, the conditions you agree to when you fill the form etc.

CRITERIA TO GET A CERTIFICATE

Average assignment score = 25% of average of best 8 assignments out of the total 12 assignments given in the course.
Exam score = 75% of the proctored certification exam score out of 100

Final score = Average assignment score + Exam score

YOU WILL BE ELIGIBLE FOR A CERTIFICATE ONLY IF AVERAGE ASSIGNMENT SCORE >=10/25 AND EXAM SCORE >= 30/75. If one of the 2 criteria is not met, you will not get the certificate even if the Final score >= 40/100.

Certificate will have your name, photograph and the score in the final exam with the breakup.It will have the logos of NPTEL and IISc Bangalore .It will be e-verifiable at nptel.ac.in/noc.

Only the e-certificate will be made available. Hard copies will not be dispatched.

Once again, thanks for your interest in our online courses and certification. Happy learning.

- NPTEL team

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