Week 1: Basics Principles of NMR; Nuclear Spin in static magnetic field
Week 2: Basics Principles continued; Chemical Shift; Factors Influencing Isotropic Chemical shifts
Week 3: NMR instrumentation and Peptide sample preparation; Overview of NMR instrument Magnet, transmitters etc
Week 4: Two-dimensional NMR And Practical Aspects for experiment; Two- dimensional correlation experiments COSY
Week 5: Peptide and Protein structure Structural features and parameters; Structural features and parameters
Week 6: Sample preparation for Protein NMR; Expression systems, Optimization of protein expression
Week 7: Multi-dimensional Heteronuclear NMR experiments; 2D Heteronuclea r NMR experiments
Week 8: Multi-dimensional Heteronuclear NMR experiments; Experiments for Backbone assignment
Week 9: Protein Structure determination from NMR data; Structure calculation methods and NMR parameters
Week 10: Protein dynamics from NMR data; Theory of spin relaxation in proteins
Week 11: Nucleic acids NMR experiments; Structural features and parameters for Nuclei acids
Week 12: DNA and structure determination from NMR data
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