Reactive Intermediates Carbene and Nitrene

By Prof. Rajarshi Samanta   |   IIT Kharagpur
Learners enrolled: 818
Reactive intermediates" is an important topic in basic organic chemistry courses. Among different reactive intermediates, carbene & nitrene being neutral and highly electron deficient species play a significant role in various organic transformations. In this course we will disclose its generation, stability, structure, reactivity etc. Next, the application of these reactive intermediates in various organic reactions will be disclosed in detail. Furthermore, the course will accommodate related assignments which might help in various competitive exams in future.

INTENDED AUDIENCE : Chemistry/Chemical Science
PREREQUISITES : Basic Organic Chemistry courses.
Course Status : Completed
Course Type : Core
Duration : 4 weeks
Category :
  • Chemistry
Credit Points : 1
Level : Undergraduate
Start Date : 24 Jan 2022
End Date : 18 Feb 2022
Enrollment Ends : 07 Feb 2022
Exam Date : 27 Mar 2022 IST

Note: This exam date is subjected to change based on seat availability. You can check final exam date on your hall ticket.

Page Visits

Course layout

Week 1  :  Structure and Reactivity of carbenes
Week 2  :  Generation of carbenes
Week 3  :  Different types of reactions with carbenes
Week 4  :  Generation and different reactions of nitrenes and related intermediates.

Books and references

1)Advanced Organic Chemistry (Part B) book by F. A. Carey and R. J. Sundberg
2) Organic Chemistry book by J. Clayden, N. Greeves and S. Warren.
3) Carbene Chemistry by W. Kirmse
4) Reactive Intermediates in Organic Chemistry by Maya Shankar Singh 

Instructor bio

Prof. Rajarshi Samanta

IIT Kharagpur
Dr. Rajarshi Samanta did his BSc (2002) and MSc (2004) from Department of Chemistry, Jadavpur University. He received his PhD from IICT, Hyderabad under the supervision of Prof. Tushar Kanti Chakraborty in 2010. After completing his postdoctoral studies under the supervision of Dr. A. P. Antonchick at Max-Planck Institute of Molecular Physiology (Dortmund, Germany), he joined at IIT Kharagpur in September 2013. His research interests include transition metal catalysed organic transformations, asymmetric synthesis, natural product synthesis.

Course certificate

The course is free to enroll and learn from. But if you want a certificate, you have to register and write the proctored exam conducted by us in person at any of the designated exam centres.
The exam is optional for a fee of Rs 1000/- (Rupees one thousand only).
Date and Time of Exams: 27 March 2022 Morning session 9am to 12 noon; Afternoon Session 2pm to 5pm.
Registration url: Announcements will be made when the registration form is open for registrations.
The online registration form has to be filled and the certification exam fee needs to be paid. More details will be made available when the exam registration form is published. If there are any changes, it will be mentioned then.
Please check the form for more details on the cities where the exams will be held, the conditions you agree to when you fill the form etc.


Average assignment score = 25% of average of best 3 assignments out of the total 4 assignments given in the course.
Exam score = 75% of the proctored certification exam score out of 100

Final score = Average assignment score + Exam score

YOU WILL BE ELIGIBLE FOR A CERTIFICATE ONLY IF AVERAGE ASSIGNMENT SCORE >=10/25 AND EXAM SCORE >= 30/75. If one of the 2 criteria is not met, you will not get the certificate even if the Final score >= 40/100.

Certificate will have your name, photograph and the score in the final exam with the breakup.It will have the logos of NPTEL and IIT Kharagpur .It will be e-verifiable at nptel.ac.in/noc.

Only the e-certificate will be made available. Hard copies will not be dispatched.

Once again, thanks for your interest in our online courses and certification. Happy learning.

- NPTEL team

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