Pericyclic Reactions and Organic Photochemistry

By Prof. Sankararaman | IIT Madras

Learners enrolled: 1645

The aim of the course is to make students familiar with the concepts and applications in two important topics in advanced organic chemistry, namely concerted organic reactions and organic photochemistry.

Pericyclic reactions are concerted organic reactions and are governed by Woodward-Hoffmann rules. Different methods of analysis of pericyclic reactions to arrive at the Woodward-Hoffmann rules will be presented. Synthetic applications and mechanisms of various pericyclic reactions will be discussed. Similarly the concepts involved in understanding organic photochemical reactions, their mechansims and applications in organic synthesis will be presented.

This course will uncover all the major topics in pericyclic reactions and organic photochemistry. In addition to lectures there will be tutorial sessions and assignments in this course.

INTENDED AUDIENCE : Core for post-graduates, Post-graduate and upper level undergraduate, Final Year BSc, MSc and PhD

PREREQUISITES : Basic course in organic chemistry, stereochemistry and reaction mechanisms

INDUSTRY SUPPORT : Pharma and fine chemical industry R&D labs,National labs such as NCL, IICT etc

Summary

Course Status :	Completed
Course Type :	Core
Language for course content :	English
Duration :	8 weeks
Category :	Chemistry
Credit Points :	2
Level :	Postgraduate
Start Date :	21 Feb 2022
End Date :	15 Apr 2022
Enrollment Ends :	21 Feb 2022
Exam Date :	23 Apr 2022 IST

Note: This exam date is subject to change based on seat availability. You can check final exam date on your hall ticket.

Page Visits

Course layout

Week1: General introduction to the course, activation of chemical reactions. thermal and photochemical methods, molecular
orbitals of conjugated polyenes and their symmetry properties, definition and classification of pericyclic reactions methods
of analyzing pericyclic reactions.

Week 2: Electrocyclic reactions – introduction, definition and classification, Woodward- Hoffmann rules for electrocyclic reactions,
Stereochemical aspects and modes of electrocyclic reactions, analysis of electrocyclic reactions by various methods,
examples of electrocyclic reactions.

Week 3: Electrocyclic (continued), Cycloaddition reactions, Woodward- Hoffmann rules for cycloaddition reactions, stereochemical
aspects and modes of cycloaddition reactions, analysis of cycloaddition reactions by various methods

Week 4: Examples of thermal and photochemical [2p+2p] cycloaddition reactions

Synthesis of cage type compounds using [2p+2p] cycloaddition reactions

Diels-Alder reaction and its variants and their syntic utility

Week 5: 1,3-Dipolar cycloaddition reactions, higher order cycloaddition reactions, sigmatropic rearrangements, Woodward Hoffmann rules
for sigmatropic rearrangements

Week 6: Sigmatropic rearrangements – examples, Claisen and Cope rearrangements

[2,3]-sigmatropic rearrangements and higher order rearrangements

Chelotropic reactions - introduction, definition and classification, Ene reaction.

Week 7: Organic photochemistry – introduction, definitions, importance
Electronic excitation and spin configurations – Jabolanski diagram

Energy transfer and electron transfer processes – quenching of excited states

Photochemistry of carbonyl compounds

Week 8: Photochemistry of olefins, enones and dienones, photochemistry of aromatic molecules, molecular oxygen and organic
photochemistry, supramolecular organic photochemistry.

Books and references

1. S. Sankararaman, Pericyclic Reactions – A textbook. Wiley-VCH, 2005.

2. I. Fleming, Pericyclic Reactions, Oxford University Press, 1999.

3. N. J. Turro, V. Ramamurthy and J. C. Scaiano, Modern molecular photochemistry of organic compounds, University Science Books, 2010.

Instructor bio

Prof. Sankararaman

IIT Madras

Prof. S. Sankararaman has 25 years of teaching and research experience at IIT Madras He teaches theory courses on organic chemistry, organometallic chemistry, spectroscopy and photochemistry to MSc and PhD students in addition to teaching basic organic and inorganic chemistry courses to B.Tech students. He has written a textbook on Pericyclic Reactions published by Wiley-VCH in 2005. His research interests are in the areas of organic and organometallic chemistry, organic synthesis and catalysis.

Course certificate

The course is free to enroll and learn from. But if you want a certificate, you have to register and write the proctored exam conducted by us in person at any of the designated exam centres.
The exam is optional for a fee of Rs 1000/- (Rupees one thousand only).
Date and Time of Exams: 23 April 2022 Morning session 9am to 12 noon; Afternoon Session 2pm to 5pm.
Registration url: Announcements will be made when the registration form is open for registrations.
The online registration form has to be filled and the certification exam fee needs to be paid. More details will be made available when the exam registration form is published. If there are any changes, it will be mentioned then.
Please check the form for more details on the cities where the exams will be held, the conditions you agree to when you fill the form etc.

CRITERIA TO GET A CERTIFICATE

Average assignment score = 25% of average of best 6 assignments out of the total 8 assignments given in the course.
Exam score = 75% of the proctored certification exam score out of 100

Final score = Average assignment score + Exam score

YOU WILL BE ELIGIBLE FOR A CERTIFICATE ONLY IF AVERAGE ASSIGNMENT SCORE >=10/25 AND EXAM SCORE >= 30/75. If one of the 2 criteria is not met, you will not get the certificate even if the Final score >= 40/100.

Certificate will have your name, photograph and the score in the final exam with the breakup.It will have the logos of NPTEL and IIT Madras .It will be e-verifiable at nptel.ac.in/noc.

Only the e-certificate will be made available. Hard copies will not be dispatched.

Once again, thanks for your interest in our online courses and certification. Happy learning.

- NPTEL team

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