Organ Printing

By Prof. Falguni Pati | IIT Hyderabad

Learners enrolled: 1029

ABOUT THE COURSE:
Printing of tissue analogs recapitulating the structure and function of native tissues are beneficial for many applications like tissue engineering, in vitro tissue modeling, cancer modeling, and for studying tissue/organ development process. Organ printing or 3D bioprinting uses a layer-by-layer manufacturing process with all the components of a tissue like cells, matrix materials and bioactive factors to produce artificial tissues. Various aspects of this technology will be described in this course starting from the fundamental of 3D Bioprinting, process parameters, bioinks used to organ-specific strategies for tissue printing. Moreover, the applications of this technology will be described with examples from recent literatures and reports.

PRE-REQUISITE: Knowledge on Biomaterials and Human Anatomy and Physiology.

INTENDED AUDIENCE: Students from Bioengineering/Biomedical Engineering/Biotechnology programs.

INDUSRTY SUPPORT: Relevant Industries of Biotechnology/Biomaterials/Tissue Engineering.

Summary

Course Status :	Completed
Course Type :	Elective
Language for course content :	English
Duration :	8 weeks
Category :	Biological Sciences & Bioengineering Bioengineering
Credit Points :	2
Level :	Postgraduate
Start Date :	25 Jul 2022
End Date :	16 Sep 2022
Enrollment Ends :	08 Aug 2022
Exam Date :	25 Sep 2022 IST

Note: This exam date is subject to change based on seat availability. You can check final exam date on your hall ticket.

Page Visits

Course layout

Week 1: Introduction to Bioprinting; different types of bioprinting techniques and their advantages and disadvantages

Week 2: 3D tissue designing and 3D tissue/organ printing; various process parameters and their role in bioprinting
Week 3: Introduction to bioinks; biomaterials used for bioink development with their merits and demerits
Week 4: Critical parameters of bioink formulations for bioprinting, modulation of bioink properties to control different processing conditions
Week 5: 3D bioprinted in vitro, in vivo, and ex vivo research models and techniques; in vitro manipulation of cells and biomaterials with a bioprinter to engineer tissues for regenerative medicine or in vitro tissue/organ models
Week 6: In situ bioprinting and 4D bioprinting with examples from recent literature
Week 7: Biofabrication-based strategies from bench-to-bed to address specific clinical problems
Week 8: Next step in bioprinting (challenges and future direction); ethical issues related to bioprinting

Books and references

Atala et al., Essentials of 3D Biofabrication and Translation. 1st edition, ISBN-13: 978-0128009727.
Zhang et al., 3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine. 1st edition, ISBN 9780128005477.
Forgacs et al., Biofabrication - Micro- and Nano-fabrication, Printing, Patterning and Assemblies, 1st Edition, ISBN 9781455728527.
Derby B. Printing and prototyping of tissues and scaffolds. Science. 2012. 338:921-6.
Seliktar D. Designing cell-compatible hydrogels for biomedical applications. Science. 2012. 336:1124-8.
Murphy SV, Atala A. 3D bioprinting of tissues and organs. Nature Biotechnology. 2014. 32:773-85.
Pati F, Gantelius J, Svahn HA. 3D Bioprinting of Tissue/Organ Models. Angewandte Chemie International Edition. 2016.55:4650-65.

Instructor bio

Prof. Falguni Pati

IIT Hyderabad

Prof. Falguni Pati is an Associate Professor in the Biomedical Engineering Department at IIT Hyderabad (IITH). He completed his Ph.D. from IIT Kharagpur and had Postdoctoral appointments in POSTECH, South Korea, and KTH, Sweden prior to joining IITH in 2015. His lab at IITH, Biofabrication and Tissue Engineering Lab (BioFabTE Lab) focuses on developing innovative tissue-engineered products and in vitro tissue/organ models with 3D bioprinting technology. His research interests include developing novel bioinks, bioprinting methods and protocol to produce tissue analogs-on-demand, and in vitro tissue/organ models. Dr. Pati designed and developed a course on Biofabrication for the postgraduate students at IITH, which is the first of its kind in India.

Course certificate

The course is free to enroll and learn from. But if you want a certificate, you have to register and write the proctored exam conducted by us in person at any of the designated exam centres.

The exam is optional for a fee of Rs 1000/- (Rupees one thousand only).

Date and Time of Exams: 25 September 2022 Morning session 9am to 12 noon; Afternoon Session 2pm to 5pm.

Registration url: Announcements will be made when the registration form is open for registrations.

The online registration form has to be filled and the certification exam fee needs to be paid. More details will be made available when the exam registration form is published. If there are any changes, it will be mentioned then.

Please check the form for more details on the cities where the exams will be held, the conditions you agree to when you fill the form etc.

CRITERIA TO GET A CERTIFICATE

Average assignment score = 25% of average of best 6 assignments out of the total 8 assignments given in the course.

Exam score = 75% of the proctored certification exam score out of 100

Final score = Average assignment score + Exam score

YOU WILL BE ELIGIBLE FOR A CERTIFICATE ONLY IF AVERAGE ASSIGNMENT SCORE >=10/25 AND EXAM SCORE >= 30/75. If one of the 2 criteria is not met, you will not get the certificate even if the Final score >= 40/100.

Certificate will have your name, photograph and the score in the final exam with the breakup.It will have the logos of NPTEL and IIT Hyderabad. It will be e-verifiable at nptel.ac.in/noc.

Only the e-certificate will be made available. Hard copies will not be dispatched.

Once again, thanks for your interest in our online courses and certification. Happy learning.

- NPTEL team