Drug Delivery: Principles and Engineering

By Prof. Rachit Agarwal | IISc

Learners enrolled: 3018

ABOUT THE COURSE:
This course introduces concepts of drug delivery to meet medical challenges. The course is designed to be modular, with each module focusing on the various aspects of drug delivery.

INTENDED AUDIENCE : Anyone in bachelors having completed two year

PREREQUISITES : A course in biochemistry, molecular biology, anatomy is recommended

INDUSTRY SUPPORT : All pharmaceuticals, hospitals and biotechnology industries

Summary

Course Status :	Completed
Course Type :	Elective
Language for course content :
Duration :	12 weeks
Category :	Biological Sciences & Bioengineering Bioengineering
Credit Points :	3
Level :	Undergraduate/Postgraduate
Start Date :	25 Jul 2022
End Date :	14 Oct 2022
Enrollment Ends :	08 Aug 2022
Exam Date :	30 Oct 2022 IST

Note: This exam date is subject to change based on seat availability. You can check final exam date on your hall ticket.

Page Visits

Course layout

Week 1 : Pharmacokinetics: Bioavailability, Elimination, Therapeutic index

Week 2 : Prodrugs, Controlled release

Week 3 : Polymers: Synthesis, properties, characterization, crystallinity and amorphousness

Week 4 : Biopolymers: Natural and Synthetic, biocompatibility, Biodegradation, commonly used biopolymers

Week 5 : Polymer-Drug conjugates, PEGylation

Week 6 : Diffusion controlled systems, Ficks laws, Reservoir systems, Non-erodible matrix systems, Bio-erodible Systems

Week 7 : Hydrogels: Physical or chemical, pore-size calculation, in-situ crosslinking

Week 8 : Nano and Micro-particles: Dendrimers, Liposomes, Micelles

Week 9 : Metal and polymeric particles, effect of particle shape, charge and elasticity

Week 10: Protein Adsorption and tissue engineering, Drug delivery in tissue engineering

Week 11: Implant associated infections, Route specific delivery: Oral, Subcutaneous, Intramuscular, transdermal, inhalation, intravenous

Week 12: Vaccines, Cancer vaccines, Cell and gene delivery, Smart responsive drug delivery, Targeted drug delivery, Nanotoxicology and market translation

Books and references

Drug Delivery: Engineering Principles for Drug Therapy, W. Mark Saltzman, Oxford University Press, 2001
Drug Delivery: Fundamentals and Applications, Anya M. Hillery and Kinam Park, 2nd Edition, CRC Press, 2016

Instructor bio

Prof. Rachit Agarwal

IISc

Rachit Agarwal Employment .Assistant Professor June 2017 present Centre for Biosystems Science and Engineering, Indian Institute of Science, Bangalore . Post-doctoral Fellow August 2013 May 2017 Andres J. Garcia, Georgia Institute of Technology, Atlanta, Georgia, USA Education . Ph.D. Biomedical Engineering May 2013 University of Texas at Austin, Texas, USA; Dissertation title: Effect of shape on cell internalization of polymeric hydrogel nanoparticles. Doctoral portfolio program in Nanoscience and Nanotechnology May 2013 University of Texas at Austin, Texas, USA . B.Tech and M.Tech (combined degree) - Biotechnology and Biochemical Engineering June 2009 Indian Institute of Technology, Kharagpur, India; Thesis Title: Crystallization and Enzyme Assay of GAPDH from TASAR Silk Worm

Course certificate

The course is free to enroll and learn from. But if you want a certificate, you have to register and write the proctored exam conducted by us in person at any of the designated exam centres.
The exam is optional for a fee of Rs 1000/- (Rupees one thousand only).
Date and Time of Exams: 30 October 2022 Morning session 9am to 12 noon; Afternoon Session 2pm to 5pm.
Registration url: Announcements will be made when the registration form is open for registrations.
The online registration form has to be filled and the certification exam fee needs to be paid. More details will be made available when the exam registration form is published. If there are any changes, it will be mentioned then.
Please check the form for more details on the cities where the exams will be held, the conditions you agree to when you fill the form etc.

CRITERIA TO GET A CERTIFICATE

Average assignment score = 25% of average of best 8 assignments out of the total 12 assignments given in the course.
Exam score = 75% of the proctored certification exam score out of 100

Final score = Average assignment score + Exam score

YOU WILL BE ELIGIBLE FOR A CERTIFICATE ONLY IF AVERAGE ASSIGNMENT SCORE >=10/25 AND EXAM SCORE >= 30/75. If one of the 2 criteria is not met, you will not get the certificate even if the Final score >= 40/100.

Certificate will have your name, photograph and the score in the final exam with the breakup.It will have the logos of NPTEL and IISc Bangalore.It will be e-verifiable at nptel.ac.in/noc.

Only the e-certificate will be made available. Hard copies will not be dispatched.

Once again, thanks for your interest in our online courses and certification. Happy learning.

- NPTEL team

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