Quantitative Methods in Chemistry

By Prof. Aasheesh , Prof. Bharathwaj Sathyamoorthy | IISER Bhopal

Learners enrolled: 1555

This course aims to train students towards appropriate scientific reporting of the experimental data and testing hypothesis using statistical analyses. It emphasizes on reproducibility of experiments and the sources of “errors” during repetitions of experiments, how to quantify and minimize wherever feasible. In the later part, it introduces the wide variety of separation techniques (for instance solvent extraction and chromatography etc.) employed for chemicals,polymers and biomolecules. Basic introduction of instrumentation involved in these techniques will also be discussed

INTENDED AUDIENCE : 3rd year B.Sc./3rd year BS-MS

PREREQUISITES : Basic Chemistry courses, basic mathematics from school 10+2 standard

INDUSTRY SUPPORT : Not approached yet, in the process.

Summary

Course Status :	Completed
Course Type :	Elective
Duration :	8 weeks
Category :	Chemistry
Credit Points :	2
Level :	Undergraduate
Start Date :	15 Feb 2021
End Date :	09 Apr 2021
Enrollment Ends :	15 Feb 2021
Exam Date :	25 Apr 2021 IST

Note: This exam date is subjected to change based on seat availability. You can check final exam date on your hall ticket.

Page Visits

Course layout

Week 1 : Chemical stoichiometry, parameters to define concentration of chemicals (normality, molarity, molality, mole-fractions, parts-per million), analytical concentration and equilibrium concentrations, p-value of concentration

Week 2 : Measurements and its statistical analyses (definition of mean, median, mode,variance, standard deviation, standard error, accuracy, precision), need for performing replicates/repeats, reproducibility. Classification and sources of errors,error propagation, scientific reporting data (significant figures), error curves

Week 3 : Hypothesis validation (null hypothesis, confidence levels, confidence intervals,one-tail test, two-tail test, use of statistical tables such as z-table, t-table, F-table,identifying outliers in data with Q-test)

Week 4 : Sampling, fitting and analysis of data (linear regression, single factor analysis of variance, least-significant difference)

Week 5 : Software-based data analysis (linear and non-linear regression)

Week 6 : Examples of data fitting and analysis (application to rate kinetics, gradient mixing,biomolecular folding)

Week 7 : Analytical separations (solvent extraction, chemical precipitation, various types of chromatography – size exclusion, ion exchange, affinity, gas, high pressure liquid chromatography, field-flow fractionation), Detectors in chromatography

Week 8 : Theoretical basis of chromatography (concept of plates, theoretical plate height,plate count, resolution, retention time, retention factor, selectivity factor),Differences between rate theory and plate theory

Books and references

1. Skoog, D. A. et al., Fundamentals of Analytical Chemistry, 9th Ed., Cengage Learning, 2013. 2. Christian, G.D., Analytical Chemistry, 6th Ed., Wiley, 2003 3. Gordus, A. A., Schaum’s Outline of Analytical Chemistry, 1st Ed., Tata-McGraw Hill, 1985

Instructor bio

Prof. Aasheesh

IISER Bhopal

Dr. Aasheesh Srivastava is currently the Head, Department of Chemistry, IISER Bhopal. He secured his Ph.D. in the field of Bio-organic Chemistry and has experience in the research of bio-inspired materials during his postdoctoral stint. Following his appointment as an Assistant Professor in IISER Bhopal in 2009, he has been teaching under- and post-graduate students and pursuing independent research in the fields of soft nanomaterials, bio-degradable polymers and drug delivery.

Prof. Bharathwaj Sathyamoorthy

Dr. Bharathwaj Sathyamoorthy secured his Ph.D. in the field of Bio-physical Chemistry and is a solution-state Nuclear Magnetic Resonance (NMR) spectroscopist by training. Following his appointment as an Assistant Professor in IISER Bhopal in 2015, he has been teaching under- and post-graduate students and pursuing independent research studying the structure and dynamics of biomolecules employing NMR.

Course certificate

The course is free to enroll and learn from. But if you want a certificate, you have to register and write the proctored exam conducted by us in person at any of the designated exam centres.
The exam is optional for a fee of Rs 1000/- (Rupees one thousand only).
Date and Time of Exams: 25 April 2021 Morning session 9am to 12 noon; Afternoon Session 2pm to 5pm.
Registration url: Announcements will be made when the registration form is open for registrations.
The online registration form has to be filled and the certification exam fee needs to be paid. More details will be made available when the exam registration form is published. If there are any changes, it will be mentioned then.
Please check the form for more details on the cities where the exams will be held, the conditions you agree to when you fill the form etc.

CRITERIA TO GET A CERTIFICATE

Average assignment score = 25% of average of best 6 assignments out of the total 8 assignments given in the course.
Exam score = 75% of the proctored certification exam score out of 100

Final score = Average assignment score + Exam score

YOU WILL BE ELIGIBLE FOR A CERTIFICATE ONLY IF AVERAGE ASSIGNMENT SCORE >=10/25 AND EXAM SCORE >= 30/75. If one of the 2 criteria is not met, you will not get the certificate even if the Final score >= 40/100.

Certificate will have your name, photograph and the score in the final exam with the breakup.It will have the logos of NPTEL and IIT Madras .It will be e-verifiable at nptel.ac.in/noc.

Only the e-certificate will be made available. Hard copies will not be dispatched.

Once again, thanks for your interest in our online courses and certification. Happy learning.

- NPTEL team

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