Aspects Of Biochemical Engineering

By Prof. Debabrata Das   |   IIT Kharagpur
Learners enrolled: 687
Biochemical Reaction Engineering is mostly deals with the most complicated life systems as compared to Chemical Reaction Engineering. To describe the behavior of any life system in terms of mathematical form is the basic essence of biochemical reaction engineering. The present course in true sense is an interdisciplinary subject since biologist, physicist, chemist, technologist and mathematician all join hand in hand to develop realistic models. This specialized subject comprises of transport processes, sophisticated advanced control system besides conventional biology, physics and mathematics. Production of biomolecules can be done broadly in two different ways namely, using enzymes and microbial cells. The present course is designed to cater all the above aspects of the subject. Students undergoing this course will be initially able to differentiate between conventional chemical reaction engineering and biochemical reaction engineering. They also develop the expertise to do the design of any biochemical process which will be very much useful for the industries.

  • Biotechnology
  • Chemical Engineering
  • Biochemical Engineering
  • Environmental Engineering
  • Biochemistry
PRE-REQUISITES: Mathematics in 10+2

  • IFB Agro Industry; IOC; ONGC
  • Dr. Reddy’s Laboratories
  • Biocon
  • United Beverages
  • Ranbaxy Lab. Ltd.
  • Phizer India. 

Course Status : Ongoing
Course Type : Core
Duration : 12 weeks
Start Date : 18 Jan 2021
End Date : 09 Apr 2021
Exam Date : 24 Apr 2021
Enrollment Ends : 01 Feb 2021
Category :
  • Biological Sciences & Bioengineering
  • Bioprocesses
Level : Undergraduate/Postgraduate

Course layout

Week 1: Microbiology, Biochemistry and Bioproducts
Week 2: Stoichiometry and Thermodynamics of biochemical reactions
Week 3: Kinetics of homogeneous chemical reactions
Week 4: Different types of bioreactors and reactor analysis
Week 5: Kinetics of enzyme catalyzed reactions using free enzymes
Week 6: Kinetics of enzyme catalyzed reactions using immobilized enzymes
Week 7: Kinetics of substrate utilization, product formation and biomass production of microbial cells
Week 8: Kinetics of substrate utilization, product formation and biomass production of microbial cells
Week 9: Design and analysis of activated sludge process and anaerobic digester. Scale up of bioreactor
Week 10:Transport phenomenon in bioprocess
Week 11:Air and medium sterilization
Week 12:Operation and Process control, Downstream processing, Economic analysis of biochemical processes and summary & conclusion

Books and references

1. Chemical Reaction Engineering, Octave Levenspiel
2. Biochemical Engineering Fundamentals by Bailey and Ollis
3. Bioprocess Engineering Principles by Doran
4. Bioprocess Engineering Basic Concepts by Shular and Kargi
5. Biochemical Engineering by Blanch and Clark
6. Biochemical Engineering by Aiba, Humphrey and Millis

Instructor bio

Prof. Debabrata Das

IIT Kharagpur
Prof. Debabrata Das pursued his doctoral studies from Indian Institute of Technology (IIT) Delhi. He is a Senior Professor at IIT Kharagpur. He was also associated as MNRE Renewable Energy Chair Professor. He has pioneered the promising R&D of Bioenergy production processes by applying fermentation technology. Prof. Das is involved in three different area of research: Gaseous energy recovery from organic wastes; algal biorefinery and CO2 sequestration; and microbial fuel cell. He is presently involved in teaching both undergraduate and post-graduate courses on Biochemical Reaction Engineering; Aspects of Biochemical Engineering; Bioprocess Plant and Equipment Design; and Bioprocess Technology for the students of Department of Biotechnology; Department of Chemical Engineering; Department of Chemistry and School Energy Science and Engineering. He has been teaching for the last 29 years. He was associated as a Biochemical Engineer in M/s. Citurgia Biochemicals Ltd., Surat and involved in citric acid production through fermentation process. Presently, he has the Google h-index of 43 for his research work. He has about 137 research publications in the peer reviewed journals and contributed more than 30 chapters in the books published by International publishers. He is the author of the books: Biohydrogen Production: Fundamentals and Technology Advances published by M/s. CRC Press, New York and Biohythane: Fuel for the future published by Pan Stanford Publishing, Singapore. He is the Editor of the book entitled Algal Biorefinery: An Integrated Approach published separately by Springer, Switzerland and Capital Publishing Company, India. Another book entitled A bioelectrochemical system that convert wastes to Watts is with the publisher.

Course certificate

The course is free to enroll and learn from. But if you want a certificate, you have to register and write the proctored exam conducted by us in person at any of the designated exam centres.
The exam is optional for a fee of Rs 1000/- (Rupees one thousand only).
Date and Time of Exams: 24 April 2021 Morning session 9am to 12 noon; Afternoon Session 2pm to 5pm.
Registration url: Announcements will be made when the registration form is open for registrations.
The online registration form has to be filled and the certification exam fee needs to be paid. More details will be made available when the exam registration form is published. If there are any changes, it will be mentioned then.
Please check the form for more details on the cities where the exams will be held, the conditions you agree to when you fill the form etc.


Average assignment score = 25% of average of best 8 assignments out of the total 12 assignments given in the course.
Exam score = 75% of the proctored certification exam score out of 100

Final score = Average assignment score + Exam score

YOU WILL BE ELIGIBLE FOR A CERTIFICATE ONLY IF AVERAGE ASSIGNMENT SCORE >=10/25 AND EXAM SCORE >= 30/75. If one of the 2 criteria is not met, you will not get the certificate even if the Final score >= 40/100.

Certificate will have your name, photograph and the score in the final exam with the breakup.It will have the logos of NPTEL and IIT Kharagpur .It will be e-verifiable at nptel.ac.in/noc.

Only the e-certificate will be made available. Hard copies will not be dispatched.

Once again, thanks for your interest in our online courses and certification. Happy learning.

- NPTEL team

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