Biomaterials for bone tissue engineering applications

By Dr. Bikramjit Basu   |   IISc Bangalore
Learners enrolled: 877
Biomaterials, recognized as a new class of materials in the Materials Science community, are being developed in last few decades for human health care. The design and development of biomaterials requires the integration of the concepts and expertise from two widely different disciplines, i.e. Materials Science & Engineering and Biological Science. The importance of the field of biomaterials is increasingly being noticed in the Materials community with the compulsory course on this subject is being taught at undergraduate and graduate level in most of the top universities around the world. In India, a compulsory course on biomaterials is being kept in the new course curriculum of undergraduate students in Department of Materials Science and Engineering at IIT Kanpur, while this instructor has taught a more elaborate course on biomaterials for the graduate students at IIT Kanpur and at IISc, Bangalore, over last one decade. This NPTEL course on “Biomaterials for Bone Tissue Engineering applications” will consist of several lectures on the basics of the cell biology and biomaterials science, followed by some case studies, illustrating various aspects of biomaterials development for orthopedic applications. The layout of this lecture series in terms of the succession of various concepts will primarily facilitate easier understanding for students and this important area of societal relevance in terms of human healthcare.

INTENDED AUDIENCE :Students of BE/ME/MSc/PhD streams
INDUSTRY SUPPORT  :Smith & Nephew/Adler Mediequip Pvt. Ltd., Pune, CIPET, Chennai
Course Status : Completed
Course Type : Elective
Duration : 8 weeks
Start Date : 29 Jul 2019
End Date : 20 Sep 2019
Exam Date : 29 Sep 2019 IST
Category :
  • Metallurgy and Material science & Mining Engineering
Credit Points : 2
Level : Undergraduate

Course layout

Week 1  : Introduction to Biomaterials and Biocompatibility
Week 2  : Defining tissue engineering scaffolds and implants
Week 3  : Structure and Properties of Proteins and Cells
Week 4  : Stem cells and Cell fate processes
Week 5  : Cell-material Interaction (in vitro and in vivo) and Clinical trials
Week 6  : Manufacturing of Biomaterials (metals, ceramics and polymers)
Week 7  : HA-based composites
Week 8  : Glass ceramics for orthopedic and dental applications, acetabular socket and femoral head, prototype development

Books and references

1. B.Basu, D.Katti and Ashok Kumar;Advanced Biomaterials: Fundamentals,Processing and Applications; John Wiley & Sons, Inc., USA (ISBN: 978-0-470-19340-2), September, 2009.

2. Biomaterials Science:An introduction to Materials in Medicine,Edited by Ratner, Hoffman,Schoet and Lemons,Second Edition:Elsevier Academic Press, 2004.

3. Biomaterials Science and Biocompatability, Fredrick H. Silver and David L. Christiansen,Piscataway,Springer, New Jersey.

4. Biological Performance of Materials: Fundamentals of Biocompatibility, Janathan Black, Marcel Dekker, Inc., New York and Basel, 1981

Instructor bio

Dr. Bikramjit Basu
is currently a full Professor at the Materials Research Center and holds Associate Faculty position at Center for Biosystems Science and Engineering, Indian Institute of Science (IISc), Bangalore. He is currently an Adjunct faculty at Indian Institute of Technology Kanpur (IITK). After his undergraduate and postgraduate degree in Metallurgical Engineering, he earned his PhD in Ceramics at Katholieke Universiteit Leuven, Belgium in March, 2001. After a brief post-doctoral stint at University of California, Santa Barbara; he joined IITK in November 2001 as Assistant Professor and was promoted to full Professor at IITK in March, 2012. Prof. Basu’s international standing and impact on the field are illustrated by his prolific publication record (more than 225 peer-reviewed journal articles, including 30 papers in journals with high impact factor (>4.0), more than 20 invited review papers/book chapters) and citation record (total citation: ~ 5,300, H-index: 41). He currently serves on editorial board of 12 SCI journals. Dr. Basu has served as a research adviser to 16 PhD students, 20 Masters students and mentored 10 young academic colleagues.

Prof. Basu’s contributions in Engineering Science have been widely recognised. He is one of the youngest recipients from the Metallurgy/Materials Science community as well as the only Biomaterial Scientist so far to receive India’s most coveted science award, Shanti Swarup Bhatnagar award (2013). He is an elected Fellow of the Indian National Academy of Engineering (2015), West Bengal Academy of Science and Technology (2014), Society for Biomaterials and Artificial Organs (2014) and National Academy of Sciences, India (2013). In 2015, he received National Bioscience award from the Government of India for unique contributions in the frontier areas of biological sciences. He remains the only Indian from India to receive the prestigious ‘Coble Award for Young Scholars’ (2008) from the American Ceramic Society.

Course certificate

  • The course is free to enroll and learn from. But if you want a certificate, you have to register and write the proctored exam conducted by us in person at any of the designated exam centres.
  • The exam is optional for a fee of Rs 1000/- (Rupees one thousand only).
  • Date and Time of Exams: 29th September 2019, Morning session 9am to 12 noon; Afternoon Session 2pm to 5pm.
  • Registration url: Announcements will be made when the registration form is open for registrations.
  • The online registration form has to be filled and the certification exam fee needs to be paid. More details will be made available when the exam registration form is published. If there are any changes, it will be mentioned then.
  • Please check the form for more details on the cities where the exams will be held, the conditions you agree to when you fill the form etc.

  • Average assignment score = 25% of average of best 6 assignments out of the total 8 assignments given in the course. 
  • Exam score = 75% of the proctored certification exam score out of 100
  • Final score = Average assignment score + Exam score

  • If one of the 2 criteria is not met, you will not get the certificate even if the Final score >= 40/100.
  • Certificate will have your name, photograph and the score in the final exam with the breakup.It will have the logos of NPTEL and IISc Bangalore. It will be e-verifiable at nptel.ac.in/noc.
  • Only the e-certificate will be made available. Hard copies are being discontinued from July 2019 semester and will not be dispatched

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