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Industrial Biotechnology

By Prof. Debabrata Das   |   IIT Kharagpur
Learners enrolled: 2667
The course aims to provide fundamental insights to exploit enzymes and microbes for the manufacturing of products which have a huge industrial significance. It uniquely blends the science and engineering with various biochemical processes to obtain products of diverse fields such as chemicals, food, bioenergy etc. The course introduces bioreactors, its types, operation methods and provides an experimental demonstration of the same. Strategies to obtain higher yields, design of the reactors and production of biofuels from microbes are thoroughly explained. Students of various disciplines such as biotechnology, chemical engineering, food engineering, and pharmaceutical industries can be benefitted from the course as it discusses the existing bioprocess applications such as wine and cheese making, antibiotics and vaccines etc. The course majorly focusses on the applications and allows students to gain practical knowledge rather than mere theory. Major bottlenecks for the operation of biochemical industries will be discussed.

INTENDED AUDIENCE: Biotechnology
                                        Chemical Engineering
                                        Biochemical Engineering
                                        Food Technology
                                        Environmental Engineering
                                        Applied Microbiology
                                        Pharmacy.
PRE-REQUISITES:         Knowledge in microbiology 
                                        Biochemistry and mathematics in 10+2 level

INDUSTRY SUPPORT:   LIST OF COMPANIES/INDUSTRY THAT WILL RECOGNIZE/VALUE THIS ONLINE COURSE
                        DuPont India
                        IFB Agra Industry
                        IOC; ONGC
                        Dr. Reddy’s Laboratories
                        Biocon
                        United beverages.
                      
Summary
Course Status : Completed
Course Type : Core
Language for course content : English
Duration : 12 weeks
Category :
  • Biological Sciences & Bioengineering
Credit Points : 3
Level : Undergraduate
Start Date : 29 Jul 2019
End Date : 18 Oct 2019
Exam Date : 16 Nov 2019 IST

Note: This exam date is subject to change based on seat availability. You can check final exam date on your hall ticket.


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Course layout

Week 1:   Introduction, Microbes and enzymes of industrial importance
Week 2:   Different types of bioreactors and bioreactor design
Week 3:   Microbial growth, substrate degradation and product formation kinetics, Tutorial 1
Week 4:   Instrumentation, Sterilization of air, media and reactor 
Week 5:   Upstream and Downstream processing
Week 6:   Production of Oxy Chemicals I: Tax and non-tax alcohol, Brewing industry, Tutorial 2
Week 7:   Production of Oxy Chemicals II: Wine making, Vinegar and citric acid production, Tutorial 3
Week 8:   Production of Oxy Chemicals III: Antibiotics: Penicillin; Streptomycin 
Week 9:   High fructose corn syrup, Cheese making, and Single cell production
Week 10: Vaccines production and Metal leaching
Week 11: Bioenergy- Gaseous fuels: Biohydrogen, Biomethane and Microbial fuel cell;
                 Liquid fuels: Bioethanol, Biodiesel and Biobutanol
Week 12: Aerobic and Anaerobic wastewater treatment processes, Tutorial 4

Books and references

1.Industrial Microbiology by Samuel Cate Prescott and Cecil Gordon Dunn
2.Biochemical Engineering Fundamentals by Bailey and Ollis
3.Bioprocess Engineering Principles by Doran
4.Bioprocess Engineering Basic Concepts by Shular and Kargi
5.Biochemical Engineering by Blanch and Clark
6.Biochemical Engineering by Aiba, Humphrey and Millis
7.A textbook of Industrial Microbiology by Wulf Crueger and Anneliese Cruegen

Instructor bio


Prof. Debabrata Das pursued his doctoral studies from Indian Institute of Technology (IIT) Delhi. He is a Senior Professor at IIT Kharagpur. He was also associated as MNRE Renewable Energy Chair Professor. He 
has pioneered the promising R&D of Bioenergy production processes by applying fermentation technology. Prof. Das is involved in three different area of research: Gaseous energy recovery from organic wastes; algal biorefinery and COsequestration; and microbial fuel cell.  He is presently involved in teaching both undergraduate and post-graduate courses on Biochemical Reaction Engineering; Aspects of Biochemical Engineering; Bioprocess Plant and Equipment Design; and Bioprocess Technology for the students of Department of Biotechnology; Department of Chemical Engineering; Department of Chemistry and School Energy Science and Engineering. He has been teaching for the last 29 years. He was associated as a Biochemical Engineer in M/s. Citurgia Biochemicals Ltd., Surat and involved in citric acid production through fermentation process. Presentl
y, he has the Google h-index of 43 for his research work. He has about 137 research publications in the peer reviewed journals and contributed more than 30 chapters in the books published by International publishers. He is the author of the books: “Biohydrogen Production: Fundamentals and Technology Advances” published by M/s. CRC Press, New York and “Biohythane: Fuel for the future” published by Pan Stanford Publishing, Singapore. He is the Editor of the book entitled “Algal Biorefinery: An Integrated Approach” published separately by Springer, Switzerland and Capital Publishing Company, India. Another book entitled “A bioelectrochemical system that convert wastes to Watts” is with the publisher.

Course certificate

  • The course is free to enroll and learn from. But if you want a certificate, you have to register and write the proctored exam conducted by us in person at any of the designated exam centers.
  • The exam is optional for a fee of Rs 1000/- (Rupees one thousand only).
  • Date and Time of Exams:16th November 2019,Morning session 9am to 12 noon; Afternoon Session 2pm to 5pm.
  • Registration url: Announcements will be made when the registration form is open for registrations.
  • The online registration form has to be filled and the certification exam fee needs to be paid. More details will be made available when the exam registration form is published. If there are any changes, it will be mentioned then.
  • Please check the form for more details on the cities where the exams will be held, the conditions you agree to when you fill the form etc.

CRITERIA TO GET A CERTIFICATE
  • Average assignment score = 25% of average of best 8 assignments out of the total 12 assignments given in the course. (use as per duration of the course)
  • Exam score = 75% of the proctored certification exam score out of 100
  • Final score = Average assignment score + Exam score

YOU WILL BE ELIGIBLE FOR A CERTIFICATE ONLY IF AVERAGE ASSIGNMENT SCORE >=10/25 AND EXAM SCORE >= 30/75. 
  • If one of the 2 criteria is not met, you will not get the certificate even if the Final score >= 40/100.
  • Certificate will have your name, photograph and the score in the final exam with the breakup.It will have the logos of NPTEL and IIT Kharagpur. It will be e-verifiable at nptel.ac.in/noc.
  • Only the e-certificate will be made available. Hard copies are being discontinued from July 2019 semester and will not be dispatched.


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