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Courses » Biochemistry

Biochemistry

ABOUT THE COURSE
This course is an introductory course that will focus on basic concepts in biochemistry. The course deals with an understanding of biological macromolecules: proteins, carbohydrates, lipids, and nucleic acids. The structure and functional roles of the macromolecules will be studied in addition to fundamentals of enzyme chemistry: kinetics, mechanisms, inhibition, structure and mechanism. The course will also touch upon the basics of membrane transport and bioenergetic principles. After completion of the course, the students should be able to understand the chemical properties and three-dimensional structure of these biological macromolecules in relationship to their biological function.

INTENDED AUDIENCE
Core course BSc/MSc/MS/PhD


PRE-REQUISITES
Basic concepts in Chemistry and Biology

COURSE INSTRUCTOR :

Professor Dasgupta is a completed her B.Sc. (Hons) in Chemistry from Presidency College, Kolkata. She obtained her M.Sc. from IIT Kanpur and Ph.D. from RPI, USA. She joined IIT Kharagpur in 1995 and started research in the areas of protein–protein, protein-small molecule interactions and protein structure analyses. The unique feature of her work is the blend of experimental protein chemistry with in-depth structural analysis. She is the recipient CRSI (Chemical research Society of India) Bronze medal (2016) and the Darshan Ranganathan Memorial Lecture Award of CRSI (2013). She was elected Fellow of the West Bengal Academy of Science and Technology (2014). Her teaching contributions range from classroom teaching, web-course development, introduction of new courses and teaching laboratories, development of curriculum and initiation of research in a new area in the department. Her NPTEL online course in Biochemistry has been very well received. She has delivered many popular lectures to scholars and students and has been invited to inspire young women to science. She is also a former member of the Women’s Scientist Scheme of the Department of Science and Technology (DST) and is currently a member of the core committee for early career scientists in Chemical Sciences of DST. She has guided 14 Ph.D. students and has over 100 publications in peer reviewed journals.


COURSE LAYOUT
Week 1. Amino Acids 
Week 2. Protein Structure 
Week 3. Protein Structure (continued) 
Week 4. Enzymes 
Week 5. Enzymes (continued) 
Week 6. Enzyme mechanisms 
Week 7. Lipids and Membranes
Week 8.
Nucleic acids
Week 9. Vitamins and Coenzymes 
Week 10. Carbohydrates 
Week 11. Bioenergetics 
Week 12. Metabolism 


SUGGESTED READING
1. Lehninger Principles of Biochemistry, 6th edition, by David L. Nelson and Michael M. Cox. 
2. Biochemistry by Voet and Voet 


Certification Exam 
* The exam is optional for a fee. 
* Date and time of exams: April 28 (Saturday) and 29 (Sunday) : Morning session 9am to 12 noon;
* Exam for this course will be available in one session on both 28 and 29 April.
* Registration url: Announcements will be made when the registration from is open fro registrations. 
* The online registration form has to be filled and the certificate exam fee needs to be paid. More details will be made available when the exam registration form is published.


Certificate

* Final score will be calculated as : 25% assignment score + 75% final exam score. 
* 25% assignment score is calculated as 25% of average of 12 weeks course: Best 8 out of 12 assignments. 
* E - certificated will be given to those who register and write the exam and score greater than or equal to 40% final score. Certificate will have        your name, photograph and the score in the final exam with the breakup. It will have the logos of NPTEL and IIT Kharagpur. It will be e-
  verifiable 
at nptel.ac.in/noc.